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Daily Zinc Supplement Cuts Infection Rate by Nearly 40 Percent in Children With Sickle Cell Anemia

A 20-milligram daily dose of zinc was found to significantly reduce infections in children who have sickle cell anemia, according to new research.

In this session of Beyond the Data, Dr. Phoebe Thorpe and Dr. Kathryn Hassell discuss sickle cell disease, what it is, and how far care, treatment, and patient outcomes have come in the last 40 years.
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In this session of Beyond the Data, Dr. Phoebe Th…      Sickle Cell Anemia    Centers for Disease Control and Prevention / Wikimedia Commons (Public domain)
By Free News Press Editorial Team
Published August 21, 2026 at 1:26 AM PDT

Children with sickle cell anemia who took 20 milligrams of zinc daily experienced nearly 40 percent fewer infections, according to research reported by Newswise. The finding points to a low-cost, accessible intervention for a condition that leaves patients highly vulnerable to serious illness.

Sickle cell anemia is an inherited blood disorder that causes red blood cells to form an abnormal crescent shape. Those misshapen cells can block blood flow, cause severe pain, and damage organs. People with the disease also have weakened immune function, making infections a leading cause of illness and death, particularly in children.

The study tested a daily 20-milligram dose of zinc as a supplement in pediatric patients with the disease. Researchers tracked infection rates and found the reduction was substantial enough to draw attention as a potential standard addition to sickle cell care.

Zinc is a mineral involved in immune system function. It is relatively inexpensive and widely available, which makes it a practical option for patients in both high-income and low-income settings. The significance of the finding extends to parts of the world where sickle cell anemia is most common and where access to complex medical treatments is limited.

The research was highlighted by Newswise as a meaningful step toward reducing the infection burden that children with sickle cell anemia face throughout their lives. Infections in these patients can escalate quickly and require hospitalization, so a preventive measure with a nearly 40 percent reduction rate carries real clinical weight.

Further research will be needed to determine how zinc supplementation fits into existing treatment protocols and whether the findings hold across different patient populations and age groups.

I was blessed with the opportunity to speak with Billy Garrett, the first NBA player diagnosed with sickle cell anemia. As a leader with sickle cell disease, doing the podcast with Billy was deeply personal because my condition hindered my stamina to play basketball and participate in other athletic
I was blessed with the opportunity to speak with …      Sickle Cell Anemia    Ike Inspiration / Wikimedia Commons (CC BY 3.0)